Edited by
Prof Dr Sriram Krishnamoorthy
Department of Urology & Renal Transplantation, Sri Ramachandra Institute of Higher Education & Research, Chennai, India.

ISBN 978-93-47485-68-8 (Print)
ISBN 978-93-47485-08-4 (eBook)
DOI: https://doi.org/10.9734/bpi/mono/978-93-47485-68-8

As clinicians, teachers, and lifelong learners, we are constantly challenged to convert evolving science into everyday care. This volume is our collective attempt to do precisely that: curate state-of-the-art urological knowledge and distil it into clear, practice-ready guidance for residents, fellows, and practising urologists alike.

A recurring theme across these chapters is precision: the insistence that our diagnoses and decisions be anchored to biology, not merely morphology or habit. The opening chapters on bladder cancer exemplify this shift. Immunohistochemistry is positioned not as a “special stain,” but as a clinical instrument—clarifying CIS versus reactive atypia; enabling luminal–basal subtyping with GATA3 and CK5/6; and improving staging with smoothelin, where millimetres determine treatment. Equally, the focused appraisal of HER2 reminds us that a receptor can be a diagnostic signal, a prognostic lens, and a therapeutic doorway. From antibody-drug conjugates to rational combinations with immunotherapy, the arc is unmistakable: biomarkers are now care pathways.

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Contents

Immunohistochemistry in Bladder Cancer: Diagnostic, Prognostic, and Molecular Subtyping Applications

Vijayanand Mani, Bhavyadeep Korrapati, Vivek Meyyappan, Velmurugan Palaniyandi, Hariharasudhan Sekar, Sriram Krishnamoorthy

DOI: 10.9734/bpi/mono/978-93-47485-68-8/CH2
Page: 11-21

HER2 in Bladder Cancer: Molecular Biology, Prognostic Value, and Emerging Therapeutic Strategies

Vijayanand Mani, Bhavyadeep Korrapati, Velmurugan Palaniyandi, Hariharasudhan Sekar, Sriram Krishnamoorthy

DOI: 10.9734/bpi/mono/978-93-47485-68-8/CH3
Page: 22-34

Scoring Systems for Inflammatory and Traumatic Urethral Strictures

Bhavyadeep Korrapati, Vijayanand Mani, Vivek Meyyappan, Velmurugan Palaniyandi, Hariharasudhan Sekar, Sriram Krishnamoorthy

DOI: 10.9734/bpi/mono/978-93-47485-68-8/CH4
Page: 35-44

Supine Percutaneous Nephrolithotomy (PCNL): Current Status

Bhavyadeep Korrapati, Vijayanand Mani, Velmurugan Palaniyandi, Hariharasudhan Sekar, Sriram Krishnamoorthy

DOI: 10.9734/bpi/mono/978-93-47485-68-8/CH5
Page: 45-58

Innovations in Flexible Ureterorenoscopy for Renal Stones

Rajan Ravichandran, Roshan Reddy, Vivek Meyyappan, Velmurugan Palaniyandi, Hariharasudhan Sekar, Sriram Krishnamoorthy

DOI: 10.9734/bpi/mono/978-93-47485-68-8/CH6
Page: 59-76

Angiogenesis in Renal Cell Carcinoma: Molecular Biology, Clinical Manifestations, and Case-Based Insights

Rajan Ravichandran, Roshan Reddy, Vivek Meyyappan, Velmurugan Palaniyandi, Hariharasudhan Sekar, Sriram Krishnamoorthy

DOI: 10.9734/bpi/mono/978-93-47485-68-8/CH7
Page: 77-91

Renal Papillary Necrosis in Acute Pyelonephritis: Pathogenesis, Diagnosis, and the Role of Relook Flexible Ureterorenoscopy

Suryaram Aravind, Punith Jain, Hariharasudhan Sekar, Velmurugan Palaniyandi, Vivek Meyyappan, Sriram Krishnamoorthy

DOI: 10.9734/bpi/mono/978-93-47485-68-8/CH8
Page: 92-110