Molecular Breeding Approaches to Enhance Crop Productivity and Mitigate Climate Change: A Critical Review

R. Muthuvijayaragavan *

Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu – 641 003, India.

E. Murugan

Department of Plant Breeding and Genetics, Agricultural College and Research Institute, Madurai, Tamil Nadu – 625 104, India.

*Author to whom correspondence should be addressed.


Abstract

Global agriculture faces a convergence of pressures from a growing population, shrinking arable land, and an increasingly erratic climate. Conventional plant breeding, reliant on phenotypic selection over successive generations, has delivered substantial genetic gains over the past century but is proving too slow and imprecise to keep pace with the rate of environmental change. Molecular breeding, encompassing marker-assisted selection, marker-assisted backcrossing, genomic selection, and genome editing, has emerged as a complementary and increasingly dominant paradigm for accelerating crop improvement while embedding resilience to drought, heat, salinity, and flooding. This review synthesises recent literature on the principal molecular breeding platforms applied to major staple and orphan crops, traces their contribution to yield stability under abiotic stress, and evaluates their role in climate change mitigation through traits such as nitrogen use efficiency, root architecture optimisation, and reduced input dependency. Particular attention is given to the integration of genomic selection with high-throughput phenotyping and multi-omics data, the expanding application of CRISPR-Cas-based genome editing for precision trait modification, and the use of speed breeding to compress generation intervals. Case studies drawn from rice, wheat, and maize illustrate how molecular tools have translated genetic knowledge into deployed cultivars, notably the submergence-tolerant Sub1 rice lineages and drought-tolerant maize hybrids released across sub-Saharan Africa. The review concludes that the future of climate-resilient crop improvement depends on the convergence of predictive breeding models, artificial intelligence, and coordinated policy frameworks that can translate laboratory advances into equitable field-level adoption.

Keywords: Molecular breeding, genomic selection, genome editing, climate resilience, abiotic stress tolerance, marker-assisted selection, crop productivity


How to Cite

Muthuvijayaragavan, R., & Murugan, E. (2026). Molecular Breeding Approaches to Enhance Crop Productivity and Mitigate Climate Change: A Critical Review. Agricultural Sciences: Techniques and Innovations Vol. 11, 1–23. https://doi.org/10.9734/bpi/asti/v11/7622