Medical Science: Updates and Prospects Vol. 2

Perforated peptic ulcer represents the second most prevalent complication associated with peptic ulcer disease, and its management is categorised into surgical and non-surgical approaches. Surgical intervention encompasses the closure of the ulcer utilising an omental patch, which can be executed through either open or laparoscopic techniques. In cases of larger ulcers, surgical resection in the form of partial gastrectomy is performed. Non-surgical treatment modalities include the administration of intravenous antibiotics, endoscopy, and stent placement, primarily reserved for patients deemed unsuitable for surgical intervention. Eradication of Helicobacter pylori is another area where intervention may enhance clinical outcomes and reduce the risk of ulcer recurrence. It is imperative that the surgical treatment of a perforated peptic ulcer is not delayed, as postponement can lead to increased mortality. This review aims to examine the role of laparoscopic surgery in the management of perforated peptic ulcers. Additionally, it explored the significance of non-operative treatment and the eradication of Helicobacter pylori in the management of perforated peptic ulcers.