https://stm2.bookpi.org/CCFLT/issue/feedClinical Chemistry Fundamentals and Laboratory Techniques2025-12-23T08:11:28+00:00Open Journal Systems<p>The book Clinical Chemistry Fundamentals and Laboratory Techniques was developed with the objective of providing a clear, comprehensive, and practical guide to the essential principles and analytical methods of clinical chemistry. Part 1 introduces the fundamentals of clinical chemistry, whereas Part 2 focuses on biomolecules such as carbohydrates, amino acids, and proteins, which are central to metabolism and routinely measured in laboratories. While Part 3 discusses the renal system, water and electrolyte balance, acid-base homeostasis, and renal anatomy to provide a detailed understanding of the body’s regulatory mechanisms, Part 4 expands into endocrinology, inborn errors of metabolism, toxicology, chromatography, and fluid analysis, some important parts of clinical chemistry. Finally, Part 5 concludes with enzymology, tumour markers, quality control, and laboratory management, highlighting both diagnostic interpretation and the operational standards crucial for reliable laboratory performance.</p>https://stm2.bookpi.org/CCFLT/article/view/733Clinical Chemistry Fundamentals and Laboratory Techniques2025-12-23T08:11:28+00:00Abazar Mohmoud Ismail Siddig[email protected]<p>Clinical Chemistry, also known as Chemical Pathology, Clinical Biochemistry, or Medical Biochemistry the branch of chemistry that is concerned with the analysis of body fluids for diagnostic and therapeutic purposes.</p> <p>Now, in clinical chemistry, there are various types of techniques applied to all body fluids to assist in diagnosis, treatment, and monitoring for many diseases.</p> <p>All biochemical tests come under chemical pathology. These are performed on any body fluids, but mostly on serum or plasma.</p> <p>This large group of tests can be categorised into sub-specialities which contain:</p> <p>General chemistry: contains commonly ordered tests such as LFT, RFT, and blood glucose tests.<br />Special chemistry: Contains elaborate techniques such as electrophoresis, chromatography, immunoassay, and tumour markers.<br />Clinical enzymology: The study of enzymes and their activities.<br />Clinical endocrinology: Responsible for the study of hormones and the diagnosis of endocrine disorders.<br />Toxicology: Responsible for the study of drugs of abuse and other chemicals.<br />Therapeutic drug monitoring: Responsible for measuring therapeutic medication levels to optimise dosage.<br />Body fluids analysis: Responsible for the chemical analysis of body fluids to diagnose a wide array of diseases.</p> <p>The primary purpose of a clinical chemistry laboratory is to facilitate the correct performance of analytic procedures that yield accurate and precise information, aiding patient diagnosis and treatment. The achievement of reliable results requires that the clinical laboratory scientist be able to use basic supplies and equipment correctly and possess an understanding of fundamental concepts critical to any analytic procedure.</p>2025-12-23T00:00:00+00:00Copyright (c) 2025 Author(s). The licensee is the publisher (BP International).